Sunday, January 29, 2012

Fluoride Health Effects Database

Fluoride Health Effects Database: Fluoride & the Thyroid

Summation - Fluoride & the Thyroid:

According to the US National Research Council, "several lines of information indicate an effect of fluoride exposure on thyroid function."

Fluoride's potential to impair thyroid function is perhaps best illustrated by the fact that -- up until the 1970s -- European doctors used fluoride as a thyroid-suppressing medication for patients with HYPER-thyroidism (over-active thyroid). Fluoride was utilized because it was found to be effective at reducing the activity of the thyroid gland - even at doses as low as 2 mg/day.

Today, many people living in fluoridated communities are ingesting doses of fluoride (1.6-6.6 mg/day) that fall within the range of doses (2 to 10 mg/day) once used by doctors to reduce thyroid activity in hyperthyroid patients.

While it may be that the thyroid in a patient with hyperthyroidism is particularly susceptible to the anti-thyroid actions of fluoride, there is concern that current fluoride exposures may be playing a role in the widespread incidence of HYPO-thyroidism (under-active thyroid) in the U.S.

Hypothyrodisim, most commonly diagnosed in women over 40, is a serious condition with a diverse range of symptoms including: fatigue, depression, weight gain, hair loss, muscle pains, increased levels of "bad" cholesterol (LDL), and heart disease.. The drug (Synthroid) used to treat hypothyroidism is now one of the top five prescribed drugs in the U.S.

As recommended by the US National Research Council: “The effects of fluoride on various aspects of endocrine function should be examined further, particularly with respect to a possible role in the development of several diseases or mental states in the United States.”

Fluoride & the Thyroid - Overviews:

Letter from Dr. Richard Shames - Letter to Palm Beach Board of County Commissioners, May 1, 2006

Health Warning: The Thyroid and Fluoride - Paul Connett, PhD, September 2003

Fluoride & the Endocrine System: Presentation to 2nd Citizens' Conference on Fluoride - Kathleen Thiessen, PhD, July 2006

History of the fluoride/iodine antagonism - Parents of Fluoride Poisoned Children, 2000-2006

Fluoride & the Thyroid - US National Research Council (2006):

“In summary, evidence of several types indicates that fluoride affects normal endocrine function or response; the effects of the fluoride-induced changes vary in degree and kind in different individuals. Fluoride is therefore an endocrine disruptor in the broad sense of altering normal endocrine function or response, although probably not in the sense of mimicking a normal hormone. The mechanisms of action remain to be worked out and appear to include both direct and indirect mechanisms, for example, direct stimulation or inhibition of hormone secretion by interference with second messenger function, indirect stimulation or inhibition of hormone secretion by effects on things such as calcium balance, and inhibition of peripheral enzymes that are necessary for activation of the normal hormone.”
SOURCE: National Research Council. (2006). Fluoride in Drinking Water: A Scientific Review of EPA's Standards. National Academies Press, Washington D.C. p 223.

“The effects of fluoride on various aspects of endocrine function should be examined further, particularly with respect to a possible role in the development of several diseases or mental states in the United States.”
SOURCE: National Research Council. (2006). Fluoride in Drinking Water: A Scientific Review of EPA's Standards. National Academies Press, Washington D.C. p 224.

“several lines of information indicate an effect of fluoride exposure on thyroid function.”
SOURCE: National Research Council. (2006). Fluoride in Drinking Water: A Scientific Review of EPA's Standards. National Academies Press, Washington D.C. p 197.

“it is difficult to predict exactly what effects on thyroid function are likely at what concentration of fluoride exposure and under what circumstances.”
SOURCE: National Research Council. (2006). Fluoride in Drinking Water: A Scientific Review of EPA's Standards. National Academies Press, Washington D.C. p 197.

“Fluoride exposure in humans is associated with elevated TSH concentrations, increased goiter prevalence, and altered T4 and T3 concentrations; similar effects on T4 and T3 are reported in experimental animals..”
SOURCE: National Research Council. (2006). Fluoride in Drinking Water: A Scientific Review of EPA's Standards. National Academies Press, Washington D.C. p 218.

“In humans, effects on thyroid function were associated with fluoride exposures of 0.05-0.13 mg/kg/day when iodine intake was adequate and 0.01-0.03 mg/kg/day when iodine intake was inadequate.”
SOURCE: National Research Council. (2006). Fluoride in Drinking Water: A Scientific Review of EPA's Standards. National Academies Press, Washington D.C. p 218.

“The recent decline in iodine intake in the United States could contribute to increased toxicity of fluoride for some individuals.”
SOURCE: National Research Council. (2006). Fluoride in Drinking Water: A Scientific Review of EPA's Standards. National Academies Press, Washington D.C. p 218.

“Intake of nutrients such as calcium and iodine often is not reported in studies of fluoride effects. The effects of fluoride on thyroid function, for instance, might depend on whether iodine intake is low, adequate, or high, or whether dietary selenium is adequate.”
SOURCE: National Research Council. (2006). Fluoride in Drinking Water: A Scientific Review of EPA's Standards. National Academies Press, Washington D.C. p 222.

Fluoride & the Thyroid - Studies Available Online:

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